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White matter abnormalities in the Hdc knockout mouse, a model of tic and OCD pathophysiology

INTRODUCTION: An inactivating mutation in the histidine decarboxylase gene (Hdc) has been identified as a rare but high-penetrance genetic cause of Tourette syndrome (TS). TS is a neurodevelopmental syndrome characterized by recurrent motor and vocal tics; it is accompanied by structural and functio...

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Detalles Bibliográficos
Autores principales: Jindachomthong, Kantiya, Yang, Chengran, Huang, Yuegao, Coman, Daniel, Rapanelli, Maximiliano, Hyder, Fahmeed, Dougherty, Joseph, Frick, Luciana, Pittenger, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731796/
https://www.ncbi.nlm.nih.gov/pubmed/36504678
http://dx.doi.org/10.3389/fnmol.2022.1037481