Gambogic acid and juglone inhibit RNase P through distinct mechanisms

The first step in transfer RNA (tRNA) maturation is the cleavage of the 5′ end of precursor tRNA (pre-tRNA) catalyzed by ribonuclease P (RNase P). RNase P is either a ribonucleoprotein complex with a catalytic RNA subunit or a protein-only RNase P (PRORP). In most land plants, algae, and Euglenozoa,...

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Detalles Bibliográficos
Autores principales: Wu Meyers, Nancy, Karasik, Agnes, Kaitany, Kipchumba, Fierke, Carol A., Koutmos, Markos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731865/
https://www.ncbi.nlm.nih.gov/pubmed/36370850
http://dx.doi.org/10.1016/j.jbc.2022.102683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731865/
https://www.ncbi.nlm.nih.gov/pubmed/36370850
http://dx.doi.org/10.1016/j.jbc.2022.102683

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