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Gambogic acid and juglone inhibit RNase P through distinct mechanisms
The first step in transfer RNA (tRNA) maturation is the cleavage of the 5′ end of precursor tRNA (pre-tRNA) catalyzed by ribonuclease P (RNase P). RNase P is either a ribonucleoprotein complex with a catalytic RNA subunit or a protein-only RNase P (PRORP). In most land plants, algae, and Euglenozoa,...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731865/ https://www.ncbi.nlm.nih.gov/pubmed/36370850 http://dx.doi.org/10.1016/j.jbc.2022.102683 |