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Teriparatide ameliorates articular cartilage degradation and aberrant subchondral bone remodeling in DMM mice

OBJECTIVE: Knee osteoarthritis (KOA) is a highly prevalent musculoskeletal disorder characterized by degeneration of cartilage and abnormal remodeling of subchondral bone (SCB). Teriparatide (PTH (1–34)) is an effective anabolic drug for osteoporosis (OP) and regulates osteoprotegerin (OPG)/receptor...

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Detalles Bibliográficos
Autores principales: Li, Guoqing, Liu, Su, Chen, Yixiao, Xu, Huihui, Qi, Tiantian, Xiong, Ao, Wang, Deli, Yu, Fei, Weng, Jian, Zeng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731868/
https://www.ncbi.nlm.nih.gov/pubmed/36514714
http://dx.doi.org/10.1016/j.jot.2022.10.015