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Insulin and IGF-1 elicit robust transcriptional regulation to modulate autophagy in astrocytes

OBJECTIVE: Insulin is a principal metabolic hormone. It regulates a plethora of metabolic pathways in peripheral tissues. The highly homologous insulin-like growth factor 1 (IGF-1), on the other hand, is important for development and growth. Recent studies have shown that insulin and IGF-1 signaling...

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Detalles Bibliográficos
Autores principales: Geffken, Shawn J., Moon, Sohyun, Smith, Catherine O., Tang, Sharon, Lee, Hiu Ham, Lewis, Kevin, Wong, Chun Wa, Huang, Yuan, Huang, Qian, Zhao, Ying-Tao, Cai, Weikang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731889/
https://www.ncbi.nlm.nih.gov/pubmed/36503893
http://dx.doi.org/10.1016/j.molmet.2022.101647