Developing an internal threshold of toxicological concern (iTTC)

BACKGROUND: Threshold of Toxicological Concern (TTC) approaches are used for chemical safety assessment and risk-based priority setting for data poor chemicals. TTCs are derived from in vivo No Observed Effect Level (NOEL) datasets involving an external administered dose from a single exposure route...

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Detalles Bibliográficos
Autores principales: Arnot, Jon A., Toose, Liisa, Armitage, James M., Sangion, Alessandro, Looky, Alexandra, Brown, Trevor N., Li, Li, Becker, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731903/
https://www.ncbi.nlm.nih.gov/pubmed/36347933
http://dx.doi.org/10.1038/s41370-022-00494-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731903/
https://www.ncbi.nlm.nih.gov/pubmed/36347933
http://dx.doi.org/10.1038/s41370-022-00494-x

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