Lysosomal cathepsins act in concert with Gasdermin-D during NAIP/NLRC4-dependent IL-1β secretion

The NAIP/NLRC4 inflammasome is classically associated with the detection of bacterial invasion to the cytosol. However, recent studies have demonstrated that NAIP/NLRC4 is also activated in non-bacterial infections, and in sterile inflammation. Moreover, in addition to the well-established model for...

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Detalles Bibliográficos
Autores principales: Branco, Laura Migliari, Amaral, Marcelo Pires, Boekhoff, Henning, de Lima, Ana Beatriz Figueiredo, Farias, Ingrid Sancho, Lage, Silvia Lucena, Pereira, Gustavo José Silva, Franklin, Bernardo Simões, Bortoluci, Karina Ramalho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731969/
https://www.ncbi.nlm.nih.gov/pubmed/36481780
http://dx.doi.org/10.1038/s41419-022-05476-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731969/
https://www.ncbi.nlm.nih.gov/pubmed/36481780
http://dx.doi.org/10.1038/s41419-022-05476-3

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