Transcriptomic changes underlying EGFR inhibitor resistance in human and mouse models of basal-like breast cancer

The goals of this study were to identify transcriptomic changes that arise in basal-like breast cancer cells during the development of resistance to epidermal growth factor receptor inhibitors (EGFRi) and to identify drugs that are cytotoxic once EGFRi resistance occurs. Human patient-derived xenogr...

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Detalles Bibliográficos
Autores principales: Rashid, Narmeen S., Boyd, David C., Olex, Amy L., Grible, Jacqueline M., Duong, Alex K., Alzubi, Mohammad A., Altman, Julia E., Leftwich, Tess J., Valentine, Aaron D., Hairr, Nicole S., Zboril, Emily K., Smith, Timothy M., Pfefferle, Adam D., Dozmorov, Mikhail G., Harrell, J. Chuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731984/
https://www.ncbi.nlm.nih.gov/pubmed/36482068
http://dx.doi.org/10.1038/s41598-022-25541-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731984/
https://www.ncbi.nlm.nih.gov/pubmed/36482068
http://dx.doi.org/10.1038/s41598-022-25541-3

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