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Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy

Chemoresistance has long been the bottleneck of ovarian cancer (OC) prognosis. It has been shown that mitochondria play a crucial role in cell response to chemotherapy and that dysregulated mitochondrial dynamics is intricately linked with diseases like OC, but the underlying mechanisms remain equiv...

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Detalles Bibliográficos
Autores principales: Meng, Yang, Qiu, Lei, Zeng, Xinyi, Hu, Xiaoyan, Zhang, Yaguang, Wan, Xiaowen, Mao, Xiaobing, Wu, Jian, Xu, Yongfeng, Xiong, Qunli, Chen, Zhixin, Zhang, Bo, Han, Junhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9731993/
https://www.ncbi.nlm.nih.gov/pubmed/36481655
http://dx.doi.org/10.1038/s41392-022-01253-y