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Lactate regulators contribute to tumor microenvironment and predict prognosis in lung adenocarcinoma
BACKGROUND: Lactic acid, as a product of glycolysis, increases tumor cell migration and the invasion of tumor cells in the tumor microenvironment. Besides this, lactic acid promotes the expression of programmed death-1 expression (PD-1) in regulatory T cells, which could cause the failure of PD-1 bl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732022/ https://www.ncbi.nlm.nih.gov/pubmed/36505423 http://dx.doi.org/10.3389/fimmu.2022.1024925 |