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Lactate regulators contribute to tumor microenvironment and predict prognosis in lung adenocarcinoma

BACKGROUND: Lactic acid, as a product of glycolysis, increases tumor cell migration and the invasion of tumor cells in the tumor microenvironment. Besides this, lactic acid promotes the expression of programmed death-1 expression (PD-1) in regulatory T cells, which could cause the failure of PD-1 bl...

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Detalles Bibliográficos
Autores principales:	Shang, Shipeng, Wang, Mi-zhou, Xing, Zhiyuan, He, Ningning, Li, Shangyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732022/ https://www.ncbi.nlm.nih.gov/pubmed/36505423 http://dx.doi.org/10.3389/fimmu.2022.1024925

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