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Yi-Shen-Hua-Shi granules inhibit diabetic nephropathy by ameliorating podocyte injury induced by macrophage-derived exosomes

Objective: To observe the therapeutic effect of Yi-Shen-Hua-Shi (YSHS) granule in podocyte damage and diabetic nephropathy (DN) proteinuria and to explore the corresponding mechanism. Methods: The db/db mice were used to establish the DN model. Serum creatinine (SCr), blood urea nitrogen (BUN), and...

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Detalles Bibliográficos
Autores principales: Liang, Mingzhu, Zhu, Xiaodong, Zhang, Di, He, Wenfang, Zhang, Jinshi, Yuan, Shizhu, He, Qiang, Jin, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732029/
https://www.ncbi.nlm.nih.gov/pubmed/36506555
http://dx.doi.org/10.3389/fphar.2022.962606