Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity

Tripartite motif (TRIM) proteins constitute a large family of RING-type E3 ligases that share a conserved domain architecture. TRIM2 and TRIM3 are paralogous class VII TRIM members that are expressed mainly in the brain and regulate different neuronal functions. Here we present a detailed structure-...

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Detalles Bibliográficos
Autores principales: Esposito, Diego, Dudley-Fraser, Jane, Garza-Garcia, Acely, Rittinger, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732051/
https://www.ncbi.nlm.nih.gov/pubmed/36481767
http://dx.doi.org/10.1038/s41467-022-35300-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732051/
https://www.ncbi.nlm.nih.gov/pubmed/36481767
http://dx.doi.org/10.1038/s41467-022-35300-7

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