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Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity
Tripartite motif (TRIM) proteins constitute a large family of RING-type E3 ligases that share a conserved domain architecture. TRIM2 and TRIM3 are paralogous class VII TRIM members that are expressed mainly in the brain and regulate different neuronal functions. Here we present a detailed structure-...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732051/ https://www.ncbi.nlm.nih.gov/pubmed/36481767 http://dx.doi.org/10.1038/s41467-022-35300-7 |