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Knockout of IL-6 mitigates cold water-immersion restraint stress-induced intestinal epithelial injury and apoptosis

BACKGROUND: Interleukin-6 (IL-6) is essential for maintaining intestinal epithelial homeostasis. Although cold water-immersion restraint (CWIR) stress is commonly used to induce in vivo gastric injury, it also affects intestinal epithelial permeability. Although IL-6 is increased in response to acut...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Duan, Chujun, Wu, Shuwen, Ma, Jingchang, Liu, Yongming, Li, Wenpeng, Wang, Tingting, Yang, Lu, Cheng, Kun, Zhuang, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732082/
https://www.ncbi.nlm.nih.gov/pubmed/36505466
http://dx.doi.org/10.3389/fimmu.2022.936689