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Atorvastatin improves cisplatin sensitivity through modulation of cholesteryl ester homeostasis in breast cancer cells

BACKGROUND: Acquired treatment resistance is a significant problem in breast cancer management, and alterations in lipid metabolism have been proposed to contribute to the development of drug resistance as well as other aspects of tumor progression. The present study aimed to identify the role of ch...

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Detalles Bibliográficos
Autores principales: Zipinotti dos Santos, Diandra, Santos Guimaraes, Isabella dos, Hakeem-Sanni, Mariam F., Cochran, Blake J., Rye, Kerry-Anne, Grewal, Thomas, Hoy, Andrew J., Rangel, Leticia B. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732177/
https://www.ncbi.nlm.nih.gov/pubmed/36481936
http://dx.doi.org/10.1007/s12672-022-00598-8