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Identification and validation of the mitochondrial function related hub genes by unsupervised machine learning and multi-omics analyses in lung adenocarcinoma

BACKGROUND: The mitochondrion and its associated genes were heavily implicated in developing and therapy tumors as the primary cellular organelle in charge of metabolic reprogramming and ferroptosis. Our work focuses on discovering new potential targets while analyzing the multi-omics data of mitoch...

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Detalles Bibliográficos
Autores principales: Jin, Xing, Zhang, Huan, Sui, Qihai, Li, Ming, Liang, Jiaqi, Hu, Zhengyang, Cheng, Ye, Zheng, Yuansheng, Chen, Zhencong, Lin, Miao, Wang, Hao, Zhan, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732315/
https://www.ncbi.nlm.nih.gov/pubmed/36506395
http://dx.doi.org/10.1016/j.heliyon.2022.e11966