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Protective effects of S100A8 on sepsis mortality: Links to sepsis risk in obesity and diabetes

Obesity and diabetes are independent risk factors for death during sepsis. S100A8, an alarmin, is related to inflammation, obesity, and diabetes. Here, we examine the role of S100A8 in sepsis of obesity and diabetes models. Injection of S100A8 prolongs the survival of septic mice induced by lethal e...

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Detalles Bibliográficos
Autores principales: Miyashita, Daisuke, Inoue, Ryota, Tsuno, Takahiro, Okuyama, Tomoko, Kyohara, Mayu, Nakahashi-Oda, Chigusa, Nishiyama, Kuniyuki, Fukushima, Setsuko, Inada, Yutaro, Togashi, Yu, Shibuya, Akira, Terauchi, Yasuo, Shirakawa, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732389/
https://www.ncbi.nlm.nih.gov/pubmed/36505926
http://dx.doi.org/10.1016/j.isci.2022.105662