Cargando…

Protective effects of S100A8 on sepsis mortality: Links to sepsis risk in obesity and diabetes

Obesity and diabetes are independent risk factors for death during sepsis. S100A8, an alarmin, is related to inflammation, obesity, and diabetes. Here, we examine the role of S100A8 in sepsis of obesity and diabetes models. Injection of S100A8 prolongs the survival of septic mice induced by lethal e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Miyashita, Daisuke, Inoue, Ryota, Tsuno, Takahiro, Okuyama, Tomoko, Kyohara, Mayu, Nakahashi-Oda, Chigusa, Nishiyama, Kuniyuki, Fukushima, Setsuko, Inada, Yutaro, Togashi, Yu, Shibuya, Akira, Terauchi, Yasuo, Shirakawa, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732389/ https://www.ncbi.nlm.nih.gov/pubmed/36505926 http://dx.doi.org/10.1016/j.isci.2022.105662

Ejemplares similares

Association between circulating SerpinB1 levels and insulin sensitivity in Japanese with type 2 diabetes: A single-center, cross-sectional, observational study
por: Kyohara, Mayu, et al.
Publicado: (2022)

Abdominal aortic calcification is associated with Fibrosis‐4 index and low body mass index in type 2 diabetes patients: A retrospective cross‐sectional study
por: Togashi, Yu, et al.
Publicado: (2022)

Soluble EGFR, a hepatokine, and adipsin, an adipokine, are biomarkers correlated with distinct aspects of insulin resistance in type 2 diabetes subjects
por: Kyohara, Mayu, et al.
Publicado: (2020)

Association of the plasma xanthine oxidoreductase activity with the metabolic parameters and vascular complications in patients with type 2 diabetes
por: Okuyama, Tomoko, et al.
Publicado: (2021)

Asymptomatic meningitis diagnosed by positron emission tomography in a patient with syndrome of inappropriate antidiuretic hormone secretion: a case report
por: Hasebe, Masanori, et al.
Publicado: (2021)

Uncoupling protein 2 and aldolase B impact insulin release by modulating mitochondrial function and Ca(2+) release from the ER
por: Inoue, Ryota, et al.
Publicado: (2022)

Immediate Glucose-Lowering Effect After the First Administration of Dulaglutide: A Retrospective, Single-Center, Observational Study
por: Terui, Sakiko, et al.
Publicado: (2021)

The Roles of the IGF Axis in the Regulation of the Metabolism: Interaction and Difference between Insulin Receptor Signaling and IGF-I Receptor Signaling
por: Okuyama, Tomoko, et al.
Publicado: (2021)

Metabolic recovery of lipodystrophy, liver steatosis, and pancreatic β cell proliferation after the withdrawal of OSI-906
por: Tajima, Kazuki, et al.
Publicado: (2017)

Identification of the matricellular protein Fibulin-5 as a target molecule of glucokinase-mediated calcineurin/NFAT signaling in pancreatic islets
por: Okuyama, Tomoko, et al.
Publicado: (2017)

Evaluation of the appropriateness of using glucometers for measuring the blood glucose levels in mice
por: Togashi, Yu, et al.
Publicado: (2016)

Influence of Timing of Insulin Initiation on Long-term Glycemic Control in Japanese Patients with Type 2 Diabetes: A Retrospective Cohort Study
por: Miyazaki, Takashi, et al.
Publicado: (2019)

DPP-4 inhibition improves early mortality, β cell function, and adipose tissue inflammation in db/db mice fed a diet containing sucrose and linoleic acid
por: Shirakawa, Jun, et al.
Publicado: (2016)

The Feasibility and Applicability of Stem Cell Therapy for the Cure of Type 1 Diabetes
por: Inoue, Ryota, et al.
Publicado: (2021)

Linagliptin Ameliorates Hepatic Steatosis via Non-Canonical Mechanisms in Mice Treated with a Dual Inhibitor of Insulin Receptor and IGF-1 Receptor
por: Okuyama, Tomoko, et al.
Publicado: (2020)

E2F1 transcription factor mediates a link between fat and islets to promote β cell proliferation in response to acute insulin resistance
por: Shirakawa, Jun, et al.
Publicado: (2022)

Tumor-derived extracellular vesicles regulate tumor-infiltrating regulatory T cells via the inhibitory immunoreceptor CD300a
por: Nakazawa, Yuta, et al.
Publicado: (2021)

Regulation of Immune Responses by the Activating and Inhibitory Myeloid-Associate Immunoglobuline-Like Receptors (MAIR) (CD300)
por: Shibuya, Akira, et al.
Publicado: (2009)

Effects of liraglutide and empagliflozin added to insulin therapy in patients with type 2 diabetes: A randomized controlled study
por: Nakaguchi, Hirotatsu, et al.
Publicado: (2020)

New diagnostic marker for sepsis: soluble CD14 subtype
por: Shirakawa, K, et al.
Publicado: (2004)

Identification and isolation of splenic tissue-resident macrophage sub-populations by flow cytometry
por: Fujiyama, Satoshi, et al.
Publicado: (2018)

Elovl6 regulates mechanical damage-induced keratinocyte death and skin inflammation
por: Nakamura, Yoshiyuki, et al.
Publicado: (2018)

2148. 100 Years of Sepsis: Using Topic Modeling to Understand Historical Themes Surrounding Sepsis
por: Doran Bostwick, A, et al.
Publicado: (2018)

The new sepsis marker, sCD14-ST, induction mechanism in the rabbit sepsis models
por: Shirakawa, K, et al.
Publicado: (2010)

Marginal zone B cells exacerbate endotoxic shock via interleukin-6 secretion induced by Fcα/μR-coupled TLR4 signalling
por: Honda, Shin-ichiro, et al.
Publicado: (2016)

β1-blocker in sepsis
por: Hasegawa, Daisuke, et al.
Publicado: (2021)

Selective and sequential loss of transcriptional factors: A hallmark of β‐cell failure in type 2 diabetes?
por: Shirakawa, Jun, et al.
Publicado: (2014)

Glucose‐ or insulin resistance‐mediated β‐cell replication: PKCζ integrates the proliferative signaling
por: Shirakawa, Jun, et al.
Publicado: (2016)

Potential linkage between dipeptidyl peptidase‐4 inhibitor use and the risk of pancreatitis/pancreatic cancer
por: Shirakawa, Jun, et al.
Publicado: (2020)

A review of sepsis-induced cardiomyopathy
por: Sato, Ryota, et al.
Publicado: (2015)

Defining and measuring suspicion of sepsis: an analysis of routine data
por: Inada-Kim, Matthew, et al.
Publicado: (2017)

All that seems sepsis is not sepsis
por: Guleria, Vivek S., et al.
Publicado: (2013)

Time to re-think the use of dobutamine in sepsis
por: Sato, Ryota, et al.
Publicado: (2017)

S100A8/A9 is the first predictive marker for neonatal sepsis
por: Pirr, Sabine, et al.
Publicado: (2021)

The Outcome of Sepsis Patients Admitted to the Intensive Care Unit: Experience of 100 Cases
por: Al-Wadees, Alaa Abood Najim, et al.
Publicado: (2021)

A clinical perspective of sepsis-associated delirium
por: Tsuruta, Ryosuke, et al.
Publicado: (2016)

The International Sepsis Forum's controversies in sepsis: how will sepsis be treated in 2051?
por: Marshall, John C
Publicado: (2002)

The International Sepsis Forum's controversies in sepsis: how will sepsis be treated in 2051?
por: Abraham, Edward
Publicado: (2002)

Apoptotic cells suppress mast cell inflammatory responses via the CD300a immunoreceptor
por: Nakahashi-Oda, Chigusa, et al.
Publicado: (2012)

The Japanese guidelines for the management of sepsis
por: Oda, Shigeto, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ih3r2pen1q9hcvvgce27q41241