Stress-induced transcriptional readthrough into neighboring genes is linked to intron retention

Exposure to certain stresses leads to readthrough transcription. Using polyA-selected RNA-seq in mouse fibroblasts subjected to heat shock, oxidative, or osmotic stress, we found that readthrough transcription can proceed into proximal downstream genes, in a phenomenon previously termed “read-in.” W...

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Detalles Bibliográficos
Autores principales: Hadar, Shani, Meller, Anatoly, Saida, Naseeb, Shalgi, Reut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732411/
https://www.ncbi.nlm.nih.gov/pubmed/36505935
http://dx.doi.org/10.1016/j.isci.2022.105543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732411/
https://www.ncbi.nlm.nih.gov/pubmed/36505935
http://dx.doi.org/10.1016/j.isci.2022.105543

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