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Stress-induced transcriptional readthrough into neighboring genes is linked to intron retention
Exposure to certain stresses leads to readthrough transcription. Using polyA-selected RNA-seq in mouse fibroblasts subjected to heat shock, oxidative, or osmotic stress, we found that readthrough transcription can proceed into proximal downstream genes, in a phenomenon previously termed “read-in.” W...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732411/ https://www.ncbi.nlm.nih.gov/pubmed/36505935 http://dx.doi.org/10.1016/j.isci.2022.105543 |