Activation of HIV-1 proviruses increases downstream chromatin accessibility

It is unclear how the activation of HIV-1 transcription affects chromatin structure. We interrogated chromatin organization both genome-wide and nearby HIV-1 integration sites using Hi-C and ATAC-seq. In conjunction, we analyzed the transcription of the HIV-1 genome and neighboring genes. We found t...

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Detalles Bibliográficos
Autores principales: Shah, Raven, Gallardo, Christian M., Jung, Yoonhee H., Clock, Ben, Dixon, Jesse R., McFadden, William M., Majumder, Kinjal, Pintel, David J., Corces, Victor G., Torbett, Bruce E., Tedbury, Philip R., Sarafianos, Stefan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732416/
https://www.ncbi.nlm.nih.gov/pubmed/36505924
http://dx.doi.org/10.1016/j.isci.2022.105490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732416/
https://www.ncbi.nlm.nih.gov/pubmed/36505924
http://dx.doi.org/10.1016/j.isci.2022.105490

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