HIV-1 infected humanized DRAGA mice develop HIV-specific antibodies despite lack of canonical germinal centers in secondary lymphoid tissues

A major barrier in the use of humanized mice as models of HIV-1 (HIV) infection is the inadequate generation of virus-specific antibody responses. Humanized DRAGA (hDRAGA) mice generate antigen-specific class switched antibodies to several pathogens, but whether they do so in HIV infection and the e...

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Detalles Bibliográficos
Autores principales: Ollerton, Matthew T., Folkvord, Joy M., Peachman, Kristina K., Shashikumar, Soumya, Morrison, Elaine B., Jagodzinski, Linda L., Peel, Sheila A., Khreiss, Mohammad, D’Aquila, Richard T., Casares, Sofia, Rao, Mangala, Connick, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732419/
https://www.ncbi.nlm.nih.gov/pubmed/36505432
http://dx.doi.org/10.3389/fimmu.2022.1047277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732419/
https://www.ncbi.nlm.nih.gov/pubmed/36505432
http://dx.doi.org/10.3389/fimmu.2022.1047277

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