Biochemical and in silico inhibition of bovine and human carbonic anhydrase-II by 1H-1,2,3-triazole analogs

A series of 1H-1,2,3-triazole analogs (7a–7d and 9a–9s) were synthesized via “click” chemistry and evaluated for in vitro carbonic anhydrase-II (bovine and human) inhibitory activity. The synthesis of intermediates, 7a and 7c, was achieved by using (S)-(-)ethyl lactate as a starting material. These...

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Detalles Bibliográficos
Autores principales: Khan, Majid, Avula, Satya Kumar, Halim, Sobia Ahsan, Waqas, Muhammad, Asmari, Mufarreh, Khan, Ajmal, Al-Harrasi, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732439/
https://www.ncbi.nlm.nih.gov/pubmed/36505753
http://dx.doi.org/10.3389/fchem.2022.1072337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732439/
https://www.ncbi.nlm.nih.gov/pubmed/36505753
http://dx.doi.org/10.3389/fchem.2022.1072337

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