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Genetic expression changes and pathologic findings associated with hyperhomocysteinemia in human autopsy brain tissue

INTRODUCTION: Vascular contributions to cognitive impairment and dementia (VCID) are a leading cause of dementia. An underappreciated, modifiable risk factor for VCID is hyperhomocysteinemia (HHcy), defined by elevated levels of plasma homocysteine, most often due to impaired B vitamin absorption in...

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Detalles Bibliográficos
Autores principales: Weekman, Erica M., Winder, Zach, Rogers, Colin B., Abner, Erin L., Sudduth, Tiffany L., Patel, Ela, Dugan, Adam J., Fister, Shuling X., Wasek, Brandi, Nelson, Peter T., Jicha, Gregory A., Bottiglieri, Teodoro, Fardo, David W., Wilcock, Donna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732462/
https://www.ncbi.nlm.nih.gov/pubmed/36514441
http://dx.doi.org/10.1002/trc2.12368