Heterogeneous nuclear ribonucleoprotein K is overexpressed in acute myeloid leukemia and causes myeloproliferation in mice via altered Runx1 splicing

Acute myeloid leukemia (AML) is driven by numerous molecular events that contribute to disease progression. Herein, we identify hnRNP K overexpression as a recurrent abnormality in AML that negatively correlates with patient survival. Overexpression of hnRNP K in murine fetal liver cells results in...

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Detalles Bibliográficos
Autores principales: Aitken, Marisa J L, Malaney, Prerna, Zhang, Xiaorui, Herbrich, Shelley M, Chan, Lauren, Benitez, Oscar, Rodriguez, Ashley G, Ma, Huaxian, Jacamo, Rodrigo, Duan, Ruizhi, Link, Todd M, Kornblau, Steven M, Kanagal-Shamanna, Rashmi, Bueso-Ramos, Carlos E, Post, Sean M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Cancer-specific RNAs and RNA Processing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732523/
https://www.ncbi.nlm.nih.gov/pubmed/36518526
http://dx.doi.org/10.1093/narcan/zcac039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732523/
https://www.ncbi.nlm.nih.gov/pubmed/36518526
http://dx.doi.org/10.1093/narcan/zcac039

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