A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1

A significant proportion of infant B-cell acute lymphoblastic leukemia (B-ALL) patients remains with a dismal prognosis due to yet undetermined mechanisms. We performed a comprehensive multicohort analysis of gene expression, gene fusions, and RNA splicing alterations to uncover molecular signatures...

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Detalles Bibliográficos
Autores principales: Closa, Adria, Reixachs-Solé, Marina, Fuentes-Fayos, Antonio C, Hayer, Katharina E, Melero, Juan L, Adriaanse, Fabienne R S, Bos, Romy S, Torres-Diz, Manuel, Hunger, Stephen P, Roberts, Kathryn G, Mullighan, Charles G, Stam, Ronald W, Thomas-Tikhonenko, Andrei, Castaño, Justo P, Luque, Raúl M, Eyras, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Cancer Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732526/
https://www.ncbi.nlm.nih.gov/pubmed/36518527
http://dx.doi.org/10.1093/narcan/zcac041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732526/
https://www.ncbi.nlm.nih.gov/pubmed/36518527
http://dx.doi.org/10.1093/narcan/zcac041

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