Efficient synthesis of α-galactosylceramide and its C-6 modified analogs

The synthesis of α-galactosylceramide (KRN7000) and its C-6 modified analogs remains a challenge due to the difficult α-1,2-cis-glycosidic bond. A non-participating benzyl (Bn) protecting group has been commonly used to favor the α-glycosylation product. Here, we report the α-selective glycosylation...

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Detalles Bibliográficos
Autores principales: Li, Huiting, Mao, Hongzhao, Chen, Chao, Xu, Ying, Meng, Shuai, Sun, Tiantian, Zong, Chengli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732566/
https://www.ncbi.nlm.nih.gov/pubmed/36505742
http://dx.doi.org/10.3389/fchem.2022.1039731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732566/
https://www.ncbi.nlm.nih.gov/pubmed/36505742
http://dx.doi.org/10.3389/fchem.2022.1039731

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