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Mice with lung airway ciliopathy develop persistent Mycobacterium abscessus lung infection and have a proinflammatory lung phenotype associated with decreased T regulatory cells

INTRODUCTION: Human pulmonary infection with non-tuberculous mycobacteria (NTM) such as Mycobacterium abscessus (Mabs) occurs in seemingly immunocompetent patients with underlying structural lung disease such as bronchiectasis in which normal ciliary function is perturbed. In addition to alterations...

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Detalles Bibliográficos
Autores principales: Nava, Audrey, Hahn, Andrew C., Wu, Terry H., Byrd, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732727/
https://www.ncbi.nlm.nih.gov/pubmed/36505420
http://dx.doi.org/10.3389/fimmu.2022.1017540