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Genetic Variation in ADAMTS13 is Related to VWF Levels, Atrial Fibrillation and Cerebral Ischemic Events

INTRODUCTION: ADAMTS13 cleaves von Willebrand factor (VWF) multimers into less active fragments. Both markers have been related to cardiovascular disease (CVD). We aimed to investigate the influence of ADAMTS13 single nucleotide polymorphisms (SNPs) on levels of ADAMTS13 and VWF, and CVD. METHODS: T...

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Detalles Bibliográficos
Autores principales: Warlo, Ellen M. K., Bratseth, Vibeke, Pettersen, Alf-Åge R., Holme, Pål Andre, Arnesen, Harald, Seljeflot, Ingebjørg, Opstad, Trine B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732802/
https://www.ncbi.nlm.nih.gov/pubmed/36474435
http://dx.doi.org/10.1177/10760296221141893