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Reduced brain activity during a working memory task in middle-aged apolipoprotein E ε4 carriers with overweight/obesity

OBJECTIVE: The apolipoprotein E ε4 (APOE ε4) allele and midlife obesity are independent risk factors for Alzheimer’s disease (AD). Both of these risk factors are also associated with differences in brain activation, as measured by blood oxygenation level-dependent (BOLD) responses, in the absence of...

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Detalles Bibliográficos
Autores principales: Drake, Jermon A., Jakicic, John M., Rogers, Renee J., Aghjayan, Sarah L., Stillman, Chelsea M., Donofry, Shannon D., Roecklein, Kathryn A., Lang, Wei, Erickson, Kirk I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732810/
https://www.ncbi.nlm.nih.gov/pubmed/36504632
http://dx.doi.org/10.3389/fnhum.2022.1001229