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Reduced brain activity during a working memory task in middle-aged apolipoprotein E ε4 carriers with overweight/obesity
OBJECTIVE: The apolipoprotein E ε4 (APOE ε4) allele and midlife obesity are independent risk factors for Alzheimer’s disease (AD). Both of these risk factors are also associated with differences in brain activation, as measured by blood oxygenation level-dependent (BOLD) responses, in the absence of...
Autores principales: | Drake, Jermon A., Jakicic, John M., Rogers, Renee J., Aghjayan, Sarah L., Stillman, Chelsea M., Donofry, Shannon D., Roecklein, Kathryn A., Lang, Wei, Erickson, Kirk I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732810/ https://www.ncbi.nlm.nih.gov/pubmed/36504632 http://dx.doi.org/10.3389/fnhum.2022.1001229 |
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