Arbaclofen extended-release tablets for spasticity in multiple sclerosis: randomized, controlled clinical trial

Baclofen, a racemic GABA-B (GABA(B)) receptor agonist, is commonly used for the management of multiple sclerosis-related spasticity but is associated with frequent dosing and poor tolerability. Arbaclofen, the active R-enantiomer of baclofen, exhibits 100- to 1000-fold greater specificity for the GA...

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Detalles Bibliográficos
Autores principales: Okuda, Darin T, Kantor, Daniel, Jaros, Mark, deVries, Tina, Hunter, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732858/
https://www.ncbi.nlm.nih.gov/pubmed/36519155
http://dx.doi.org/10.1093/braincomms/fcac300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732858/
https://www.ncbi.nlm.nih.gov/pubmed/36519155
http://dx.doi.org/10.1093/braincomms/fcac300

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