Comprehensive Multidimensional Liquid Chromatography–Mass Spectrometry for the Characterization of Charge Variants of a Bispecific Antibody

[Image: see text] Identification and further characterization of antibody charge variants is a crucial step during biopharmaceutical drug development, particularly with regard to the increasing complexity of novel antibody formats. As a standard analytical approach, manual offline fractionation of c...

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Detalles Bibliográficos
Autores principales: Grunert, Ingrid, Heinrich, Katrin, Hingar, Michael, Ernst, Juliane, Winter, Martin, Bomans, Katrin, Wagner, Katharina, Fevre, Arnaud, Reusch, Dietmar, Wuhrer, Manfred, Bulau, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732868/
https://www.ncbi.nlm.nih.gov/pubmed/36442848
http://dx.doi.org/10.1021/jasms.2c00296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732868/
https://www.ncbi.nlm.nih.gov/pubmed/36442848
http://dx.doi.org/10.1021/jasms.2c00296

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