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Role of Hydrophobicity at the N-Terminal Region of Aβ42 in Secondary Nucleation
[Image: see text] The self-assembly of the amyloid β 42 (Aβ42) peptide is linked to Alzheimer’s disease, and oligomeric intermediates are linked to neuronal cell death during the pathology of the disease. These oligomers are produced prolifically during secondary nucleation, by which the aggregation...
Autores principales: | Thacker, Dev, Willas, Amanda, Dear, Alexander J., Linse, Sara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9732875/ https://www.ncbi.nlm.nih.gov/pubmed/36411082 http://dx.doi.org/10.1021/acschemneuro.2c00504 |
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