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A green and efficient synthetic methodology towards the synthesis of 1-allyl-6-chloro-4-oxo-1,4-dihydroquinoline-3-carboxamide derivatives

Quinolone is a privileged scaffold in medicinal chemistry and 4-Quinolone-3-Carboxamides have been reported to harbor vast therapeutic potential. However, conversion of N-1 substituted 4-Quinolone 3-Carboxylate to its corresponding carbamates is highly restrictive. This motivated us to adopt a much...

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Detalles Bibliográficos
Autores principales: Gill, Muhammad Shoaib Ali, Azzman, Nursyuhada, Hassan, Sharifah Syed, Shah, Syed Adnan Ali, Ahemad, Nafees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733071/
https://www.ncbi.nlm.nih.gov/pubmed/36482476
http://dx.doi.org/10.1186/s13065-022-00902-1