Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD

Neutralizing antibodies (NAbs) hold great promise for clinical interventions against SARS-CoV-2 variants of concern (VOCs). Understanding NAb epitope-dependent antiviral mechanisms is crucial for developing vaccines and therapeutics against VOCs. Here we characterized two potent NAbs, EH3 and EH8, i...

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Detalles Bibliográficos
Autores principales: Chen, Yaozong, Prévost, Jérémie, Ullah, Irfan, Romero, Hugo, Lisi, Veronique, Tolbert, William D., Grover, Jonathan R., Ding, Shilei, Gong, Shang Yu, Beaudoin-Bussières, Guillaume, Gasser, Romain, Benlarbi, Mehdi, Vézina, Dani, Anand, Sai Priya, Chatterjee, Debashree, Goyette, Guillaume, Grunst, Michael W., Yang, Ziwei, Bo, Yuxia, Zhou, Fei, Béland, Kathie, Bai, Xiaoyun, Zeher, Allison R., Huang, Rick K., Nguyen, Dung N., Sherburn, Rebekah, Wu, Di, Piszczek, Grzegorz, Paré, Bastien, Matthies, Doreen, Xia, Di, Richard, Jonathan, Kumar, Priti, Mothes, Walther, Côté, Marceline, Uchil, Pradeep D., Lavallée, Vincent-Philippe, Smith, Martin A., Pazgier, Marzena, Haddad, Elie, Finzi, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733284/
https://www.ncbi.nlm.nih.gov/pubmed/36514310
http://dx.doi.org/10.1016/j.isci.2022.105783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733284/
https://www.ncbi.nlm.nih.gov/pubmed/36514310
http://dx.doi.org/10.1016/j.isci.2022.105783

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