A bispecific, crosslinking lectibody activates cytotoxic T cells and induces cancer cell death

BACKGROUND: Aberrant glycosylation patterns play a crucial role in the development of cancer cells as they promote tumor growth and aggressiveness. Lectins recognize carbohydrate antigens attached to proteins and lipids on cell surfaces and represent potential tools for application in cancer diagnos...

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Detalles Bibliográficos
Autores principales: Rosato, Francesca, Pasupuleti, Rajeev, Tomisch, Jana, Meléndez, Ana Valeria, Kolanovic, Dajana, Makshakova, Olga N., Wiltschi, Birgit, Römer, Winfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733292/
https://www.ncbi.nlm.nih.gov/pubmed/36494671
http://dx.doi.org/10.1186/s12967-022-03794-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733292/
https://www.ncbi.nlm.nih.gov/pubmed/36494671
http://dx.doi.org/10.1186/s12967-022-03794-w

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