DAD3 targets ACE2 to inhibit the MAPK and NF-κB signalling pathways and protect against LPS-induced inflammation in bovine mammary epithelial cells

The protective arm of the renin-angiotensin system (RAS), the ACE 2/Ang-(1–7)/MasR axis, has become a new anti-inflammatory target. As a specific activator of ACE2, diminazene aceturate (DA) can promote anti-inflammatory effects by regulating the ACE2/Ang-(1–7)/MasR axis. However, due to the reporte...

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Detalles Bibliográficos
Autores principales: Zhang, Xiangjun, Jia, Fang, Ma, Weiwu, Li, Xueqiang, Zhou, Xuezhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733329/
https://www.ncbi.nlm.nih.gov/pubmed/36482404
http://dx.doi.org/10.1186/s13567-022-01122-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733329/
https://www.ncbi.nlm.nih.gov/pubmed/36482404
http://dx.doi.org/10.1186/s13567-022-01122-0

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