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Identification of a novel ER-NFĸB-driven stem-like cell population associated with relapse of ER+ breast tumors

BACKGROUND: Up to 40% of patients with estrogen receptor-positive (ER+) breast cancer experience relapse. This can be attributed to breast cancer stem cells (BCSCs), which are known to be involved in therapy resistance, relapse, and metastasis. Therefore, there is an urgent need to identify genes/pa...

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Detalles Bibliográficos
Autores principales: Semina, Svetlana E., Alejo, Luis H., Chopra, Shivani, Kansara, Nidhi S., Kastrati, Irida, Sartorius, Carol A., Frasor, Jonna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733334/
https://www.ncbi.nlm.nih.gov/pubmed/36482488
http://dx.doi.org/10.1186/s13058-022-01585-1