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Genetic variation in histone modifications and gene expression identifies regulatory variants in the mammary gland of cattle

BACKGROUND: Causal variants for complex traits, such as eQTL are often found in non-coding regions of the genome, where they are hypothesised to influence phenotypes by regulating gene expression. Many regulatory regions are marked by histone modifications, which can be assayed by chromatin immunopr...

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Detalles Bibliográficos
Autores principales: Prowse-Wilkins, Claire P., Lopdell, Thomas J., Xiang, Ruidong, Vander Jagt, Christy J., Littlejohn, Mathew D., Chamberlain, Amanda J., Goddard, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733386/
https://www.ncbi.nlm.nih.gov/pubmed/36482302
http://dx.doi.org/10.1186/s12864-022-09002-9