PRState: Incorporating genetic ancestry in prostate cancer risk scores for men of African ancestry

BACKGROUND: Prostate cancer (PrCa) is one of the most genetically driven solid cancers with heritability estimates as high as 57%. Men of African ancestry are at an increased risk of PrCa; however, current polygenic risk score (PRS) models are based on European ancestry groups and may not be broadly...

Descripción completa

Detalles Bibliográficos
Autores principales: Pagadala, Meghana S., Linscott, Joshua A., Talwar, James V., Seibert, Tyler M., Rose, Brent, Lynch, Julie, Panizzon, Matthew, Hauger, Richard, Hansen, Moritz H., Sammon, Jesse D., Hayn, Matthew H., Kader, Karim, Carter, Hannah, Ryan, Stephen T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733391/
https://www.ncbi.nlm.nih.gov/pubmed/36494783
http://dx.doi.org/10.1186/s12885-022-10258-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733391/
https://www.ncbi.nlm.nih.gov/pubmed/36494783
http://dx.doi.org/10.1186/s12885-022-10258-3

Ejemplares similares