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A Poisson reduced-rank regression model for association mapping in sequencing data
BACKGROUND: Single-cell RNA-sequencing (scRNA-seq) technologies allow for the study of gene expression in individual cells. Often, it is of interest to understand how transcriptional activity is associated with cell-specific covariates, such as cell type, genotype, or measures of cell health. Tradit...
Autores principales: | Fitzgerald, Tiana, Jones, Andrew, Engelhardt, Barbara E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733401/ https://www.ncbi.nlm.nih.gov/pubmed/36482321 http://dx.doi.org/10.1186/s12859-022-05054-6 |
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