A comparison of clinical development pathways to advance tuberculosis regimen development

BACKGROUND: Current tuberculosis (TB) regimen development pathways are slow and in urgent need of innovation. We investigated novel phase IIc and seamless phase II/III trials utilizing multi-arm multi-stage and Bayesian response adaptive randomization trial designs to select promising combination re...

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Detalles Bibliográficos
Autores principales: Chang, V., Phillips, P. P. J., Imperial, M. Z., Nahid, P., Savic, R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733404/
https://www.ncbi.nlm.nih.gov/pubmed/36494644
http://dx.doi.org/10.1186/s12879-022-07846-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733404/
https://www.ncbi.nlm.nih.gov/pubmed/36494644
http://dx.doi.org/10.1186/s12879-022-07846-w

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