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Immunogenomic correlates of immune-related adverse events for anti–programmed cell death 1 therapy

Despite impressive antitumor efficacy of programmed cell death 1 (PD-1) inhibitors, this inhibition can induce mild to severe autoimmune toxicities, termed immune-related adverse events (irAEs). Yet, predictive pretreatment biomarkers for irAEs development across cancer types remain elusive. We firs...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Shi, Yuankai, Han, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733471/
https://www.ncbi.nlm.nih.gov/pubmed/36505471
http://dx.doi.org/10.3389/fimmu.2022.1032221