A GATA6-centred gene regulatory network involving HNFs and ΔNp63 controls plasticity and immune escape in pancreatic cancer

OBJECTIVE: Molecular taxonomy of tumours is the foundation of personalised medicine and is becoming of paramount importance for therapeutic purposes. Four transcriptomics-based classification systems of pancreatic ductal adenocarcinoma (PDAC) exist, which consistently identified a subtype of highly...

Descripción completa

Detalles Bibliográficos
Autores principales: Kloesch, Bernhard, Ionasz, Vivien, Paliwal, Sumit, Hruschka, Natascha, Martinez de Villarreal, Jaime, Öllinger, Rupert, Mueller, Sebastian, Dienes, Hans Peter, Schindl, Martin, Gruber, Elisabeth S, Stift, Judith, Herndler-Brandstetter, Dietmar, Lomberk, Gwen A, Seidler, Barbara, Saur, Dieter, Rad, Roland, Urrutia, Raul A, Real, Francisco X, Martinelli, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Pancreas
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733634/
https://www.ncbi.nlm.nih.gov/pubmed/33846140
http://dx.doi.org/10.1136/gutjnl-2020-321397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733634/
https://www.ncbi.nlm.nih.gov/pubmed/33846140
http://dx.doi.org/10.1136/gutjnl-2020-321397

Ejemplares similares