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A GATA6-centred gene regulatory network involving HNFs and ΔNp63 controls plasticity and immune escape in pancreatic cancer
OBJECTIVE: Molecular taxonomy of tumours is the foundation of personalised medicine and is becoming of paramount importance for therapeutic purposes. Four transcriptomics-based classification systems of pancreatic ductal adenocarcinoma (PDAC) exist, which consistently identified a subtype of highly...
Autores principales: | Kloesch, Bernhard, Ionasz, Vivien, Paliwal, Sumit, Hruschka, Natascha, Martinez de Villarreal, Jaime, Öllinger, Rupert, Mueller, Sebastian, Dienes, Hans Peter, Schindl, Martin, Gruber, Elisabeth S, Stift, Judith, Herndler-Brandstetter, Dietmar, Lomberk, Gwen A, Seidler, Barbara, Saur, Dieter, Rad, Roland, Urrutia, Raul A, Real, Francisco X, Martinelli, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733634/ https://www.ncbi.nlm.nih.gov/pubmed/33846140 http://dx.doi.org/10.1136/gutjnl-2020-321397 |
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