Autoinhibition and activation mechanisms revealed by the triangular-shaped structure of myosin Va

As the prototype of unconventional myosin motor family, myosin Va (MyoVa) transport cellular cargos along actin filaments in diverse cellular processes. The off-duty MyoVa adopts a closed and autoinhibited state, which can be relieved by cargo binding. The molecular mechanisms governing the autoinhi...

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Detalles Bibliográficos
Autores principales: Niu, Fengfeng, Liu, Yong, Sun, Kang, Xu, Shun, Dong, Jiayuan, Yu, Cong, Yan, Kaige, Wei, Zhiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733927/
https://www.ncbi.nlm.nih.gov/pubmed/36490350
http://dx.doi.org/10.1126/sciadv.add4187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733927/
https://www.ncbi.nlm.nih.gov/pubmed/36490350
http://dx.doi.org/10.1126/sciadv.add4187

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