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Single-virus tracking reveals variant SARS-CoV-2 spike proteins induce ACE2-independent membrane interactions

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) became a global health crisis after its emergence in 2019. Replication of the virus is initiated by binding of the viral spike (S) protein to human angiotensin-converting enzyme 2 (ACE2) on the target cell surface. Mutations acquired by SA...

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Detalles Bibliográficos
Autores principales: Christie, Shaun M., Tada, Takuya, Yin, Yandong, Bhardwaj, Amit, Landau, Nathaniel R., Rothenberg, Eli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733935/
https://www.ncbi.nlm.nih.gov/pubmed/36490345
http://dx.doi.org/10.1126/sciadv.abo3977