NFKB2 haploinsufficiency identified via screening for IFN-α2 autoantibodies in children and adolescents hospitalized with SARS-CoV-2–related complications

BACKGROUND: Autoantibodies against type I IFNs occur in approximately 10% of adults with life-threatening coronavirus disease 2019 (COVID-19). The frequency of anti-IFN autoantibodies in children with severe sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is unknow...

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Detalles Bibliográficos
Autores principales: Bodansky, Aaron, Vazquez, Sara E., Chou, Janet, Novak, Tanya, Al-Musa, Amer, Young, Cameron, Newhams, Margaret, Kucukak, Suden, Zambrano, Laura D., Mitchell, Anthea, Wang, Chung-Yu, Moffitt, Kristin, Halasa, Natasha B., Loftis, Laura L., Schwartz, Stephanie P., Walker, Tracie C., Mack, Elizabeth H., Fitzgerald, Julie C., Gertz, Shira J., Rowan, Courtney M., Irby, Katherine, Sanders, Ronald C., Kong, Michele, Schuster, Jennifer E., Staat, Mary A., Zinter, Matt S., Cvijanovich, Natalie Z., Tarquinio, Keiko M., Coates, Bria M., Flori, Heidi R., Dahmer, Mary K., Crandall, Hillary, Cullimore, Melissa L., Levy, Emily R., Chatani, Brandon, Nofziger, Ryan, Geha, Raif S., DeRisi, Joseph, Campbell, Angela P., Anderson, Mark, Randolph, Adrienne G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology 2023
Materias:
Covid-19
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733962/
https://www.ncbi.nlm.nih.gov/pubmed/36509151
http://dx.doi.org/10.1016/j.jaci.2022.11.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733962/
https://www.ncbi.nlm.nih.gov/pubmed/36509151
http://dx.doi.org/10.1016/j.jaci.2022.11.020

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